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Symbol Name ID |
Tox
thymocyte selection-associated high mobility group box MGI:2181659 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | increased spleen weight |
abnormal CD4-positive T cell differentiation |
abnormal positive T cell selection |
decreased NK cell number |
abnormal T cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased NK T cell number |
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology |
abnormal CD8-positive, alpha beta T cell morphology |
abnormal spleen morphology |
decreased cytotoxic T cell cytolysis |
decreased Peyer's patch number |
small Peyer's patches |
absent mesenteric lymph nodes |
absent axillary lymph nodes |
absent inguinal lymph nodes |
absent popliteal lymph nodes |
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| Availability | Mouse Genotype | |||||||||||||||||
| Toxtm1.1Kay/Toxtm1.1Kay | ||||||||||||||||||
| Tg(Tox)1Kay/? Toxtm1.1Kay/Toxtm1.1Kay |
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| Toxtm1b(KOMP)Wtsi/Toxtm1b(KOMP)Wtsi | ||||||||||||||||||
| Toxtm1Kay/Toxtm1Kay Tg(Lck-cre)1Cwi/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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